You should not be using ComboFix unless specifically instructed to do so by a Malware Removal Expert who can interpret the logs. It is a powerful tool intended by its creator to be "used under the guidance and supervision of an expert.
Using this tool incorrectly could lead to disastrous problems with your operating system such as preventing it from ever starting again. When issues arise due to complex malware infections, possible false detections, problems running ComboFix or with other security tools causing conflicts, experts are usually aware of them and can advise what should or should not be done while providing individual assistance. Those attempting to use ComboFix on their own do not have such information and are at risk when running the tool in an unsupervised environment.
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http://kb.eset.com/esetkb/index?page=content&id=SOLN146............................................................................................