Cant access hard drive in any mode, due to virus?!

Desktop contains a virus.Not sure which.
Tried removing it, by setting default re-boot to safe mode.
Now unable to re-boot in any mode.
Tried f8 in last known configuration, safe mode, safe with prompt etc.
Tried Operating system disk,after loading components,got system error and re-boot message.

Installed new drive /as master/ and infected one /as slave/.
The system does not operate when two are connected.
In fact the "name" of the infected drive has changed in BIOS!?
Any ideas on how to recover data from this mess?

Markus

Please download the current version of HijackThis from HERE

• Double click and run the installer.
  
• It will install to C:\Program Files\Trend Micro\HijackThis\hijackthis.exe
  
• After installing, you should get the user agreement, press accept and Hijack This will run.
  
• Select Do a system scan and save a log file. This will open a notepad file of everything Hijack This found, copy and paste it back here.