Cannot run dds.scr/system sercurity removal problem

Should I take off Spybot, and Adsgone? And should I stop Windows Defender?

Don't remove Windows Defender, but remove Spybot/Adsgone.

Thank you very much for your help. Is the Avira going to expire after a year? Would you suggest I try the premium? There is a free offer through trial pay.

No, the free version never expires. I use it myself.