startup error message windows cannot find winsit.exe - suspected malware

Thanks for your attention I get the following message every time the machine starts up

Windows cannot find system32\WinSit.exe

this in itself is not an issue but it would be good to clean it off and there are no signs of infection when running avg

HJT output below if it helps

Many many thanks

Ian

Logfile of Trend Micro HijackThis v2.0.2
Scan saved at 11:21:53, on 17/02/2010
Platform: Windows XP SP3 (WinNT 5.01.2600)
MSIE: Internet Explorer v8.00 (8.00.6001.18702)
Boot mode: Normal

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\spoolsv.exe
C:\Program Files\Common Files\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
C:\Program Files\Common Files\Autodesk Shared\Service\AdskScSrv.exe
C:\PROGRA~1\AVG\AVG8\avgwdsvc.exe
C:\Program Files\Bonjour\mDNSResponder.exe
C:\Program Files\Autodesk\3ds Max 2008\mentalray\satellite\raysat_3dsMax2008_32server.exe
C:\Program Files\Microsoft SQL Server\MSSQL.1\MSSQL\Binn\sqlservr.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\Common Files\Protexis\License Service\PsiService_2.exe
C:\Program Files\Microsoft SQL Server\90\Shared\sqlwriter.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\Explorer.exe
C:\Program Files\Viewpoint\Common\ViewpointService.exe
C:\PROGRA~1\AVG\AVG8\avgrsx.exe
C:\WINDOWS\system32\Tablet.exe
C:\WINDOWS\system32\WTablet\TabUserW.exe
C:\WINDOWS\system32\Tablet.exe
C:\PROGRA~1\AVG\AVG8\avgtray.exe
C:\Program Files\ACT\Act for Windows\Act.Outlook.Service.exe
C:\WINDOWS\system32\ctfmon.exe
C:\Program Files\Viewpoint\Viewpoint Manager\ViewMgr.exe
C:\WINDOWS\system32\wuauclt.exe
C:\Program Files\Mozilla Firefox\firefox.exe
C:\Program Files\AVG\AVG8\avgui.exe
C:\Program Files\AVG\AVG8\avgscanx.exe
C:\Program Files\AVG\AVG8\avgcsrvx.exe
C:\PROGRA~1\MICROS~2\OFFICE11\OUTLOOK.EXE
C:\Program Files\AVG\AVG8\avgcsrvx.exe
C:\Program Files\Microsoft Office\OFFICE11\WINWORD.EXE
C:\Program Files\Trend Micro\HijackThis\HijackThis.exe

R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page =
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://go.microsoft.com/fwlink/?LinkId=69157
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://go.microsoft.com/fwlink/?LinkId=54896
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://go.microsoft.com/fwlink/?LinkId=69157
R1 - HKCU\Software\Microsoft\Internet Connection Wizard,ShellNext = http://go.microsoft.com/fwlink/?LinkId=74005
F2 - REG:system.ini: Shell=Explorer.exe C:\WINDOWS\system32\WinSit.exe
O2 - BHO: WormRadar.com IESiteBlocker.NavFilter - {3CA2F312-6F6E-4B53-A66E-4E65E497C8C0} - C:\Program Files\AVG\AVG8\avgssie.dll
O2 - BHO: Spybot-S&D IE Protection - {53707962-6F74-2D53-2644-206D7942484F} - C:\Program Files\Spybot - Search & Destroy\SDHelper.dll
O2 - BHO: AVG Security Toolbar - {A057A204-BACC-4D26-9990-79A187E2698E} - C:\PROGRA~1\AVG\AVG8\AVGTOO~1.DLL
O2 - BHO: Google Toolbar Helper - {AA58ED58-01DD-4d91-8333-CF10577473F7} - C:\Program Files\Google\Google Toolbar\GoogleToolbar_32.dll
O2 - BHO: Google Toolbar Notifier BHO - {AF69DE43-7D58-4638-B6FA-CE66B5AD205D} - C:\Program Files\Google\GoogleToolbarNotifier\5.3.4501.1418\swg.dll
O2 - BHO: Google Dictionary Compression sdch - {C84D72FE-E17D-4195-BB24-76C02E2E7C4E} - C:\Program Files\Google\Google Toolbar\Component\fastsearch_B7C5AC242193BB3E.dll
O2 - BHO: Act.UI.InternetExplorer.Plugins.AttachFile.CAttachFile - {D5233FCD-D258-4903-89B8-FB1568E7413D} - mscoree.dll (file missing)
O3 - Toolbar: Adobe PDF - {47833539-D0C5-4125-9FA8-0819E2EAAC93} - C:\Program Files\Adobe\Acrobat 8.0\Acrobat\AcroIEFavClient.dll
O3 - Toolbar: AVG Security Toolbar - {A057A204-BACC-4D26-9990-79A187E2698E} - C:\PROGRA~1\AVG\AVG8\AVGTOO~1.DLL
O3 - Toolbar: Google Toolbar - {2318C2B1-4965-11d4-9B18-009027A5CD4F} - C:\Program Files\Google\Google Toolbar\GoogleToolbar_32.dll
O4 - HKLM\..\Run: [AVG8_TRAY] C:\PROGRA~1\AVG\AVG8\avgtray.exe
O4 - HKLM\..\Run: [Act.Outlook.Service] "C:\Program Files\ACT\Act for Windows\Act.Outlook.Service.exe"
O4 - HKLM\..\Run: [Act! Preloader] "C:\Program Files\ACT\Act for Windows\ActSage.exe" -preload
O4 - HKCU\..\Run: [CTFMON.EXE] C:\WINDOWS\system32\ctfmon.exe
O4 - HKUS\S-1-5-19\..\Run: [CTFMON.EXE] C:\WINDOWS\system32\CTFMON.EXE (User 'LOCAL SERVICE')
O4 - HKUS\S-1-5-20\..\Run: [CTFMON.EXE] C:\WINDOWS\system32\CTFMON.EXE (User 'NETWORK SERVICE')
O4 - HKUS\S-1-5-18\..\Run: [CTFMON.EXE] C:\WINDOWS\system32\CTFMON.EXE (User 'SYSTEM')
O4 - HKUS\.DEFAULT\..\Run: [CTFMON.EXE] C:\WINDOWS\system32\CTFMON.EXE (User 'Default user')
O4 - Global Startup: Adobe Gamma Loader.lnk = C:\Program Files\Common Files\Adobe\Calibration\Adobe Gamma Loader.exe
O9 - Extra button: Attach Web page to ACT! contact - {6F431AC3-364A-478b-BBDB-89C7CE1B18F6} - mscoree.dll (file missing)
O9 - Extra 'Tools' menuitem: Attach Web page to ACT! contact... - {6F431AC3-364A-478b-BBDB-89C7CE1B18F6} - mscoree.dll (file missing)
O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~1\MICROS~2\OFFICE11\REFIEBAR.DLL
O9 - Extra button: (no name) - {DFB852A3-47F8-48C4-A200-58CAB36FD2A2} - C:\Program Files\Spybot - Search & Destroy\SDHelper.dll
O9 - Extra 'Tools' menuitem: Spybot - Search && Destroy Configuration - {DFB852A3-47F8-48C4-A200-58CAB36FD2A2} - C:\Program Files\Spybot - Search & Destroy\SDHelper.dll
O9 - Extra button: (no name) - {e2e2dd38-d088-4134-82b7-f2ba38496583} - C:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O9 - Extra 'Tools' menuitem: @xpsp3res.dll,-20001 - {e2e2dd38-d088-4134-82b7-f2ba38496583} - C:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O16 - DPF: {03F998B2-0E00-11D3-A498-00104B6EB52E} (MetaStreamCtl Class) - https://components.viewpoint.com/MTSInstallers/MetaStream3.cab?url=http://www.astonmartin.com/configurator/db9volante_load.html
O16 - DPF: {1ED48504-8834-11D5-AC75-0008C73FD642} - file:///C:/PTC/proeWildfire%203.0/i486_nt/obj/pvx_install.exe
O16 - DPF: {6E32070A-766D-4EE6-879C-DC1FA91D2FC3} (MUWebControl Class) - http://update.microsoft.com/microsoftupdate/v6/V5Controls/en/x86/client/muweb_site.cab?1181744785187
O16 - DPF: {D27CDB6E-AE6D-11CF-96B8-444553540000} (Shockwave Flash Object) - http://fpdownload2.macromedia.com/get/shockwave/cabs/flash/swflash.cab
O16 - DPF: {E06E2E99-0AA1-11D4-ABA6-0060082AA75C} (GpcContainer Class) - https://attwm.webex.com/client/T25L10NSP41EP2-shared-prod/webex/ieatgpc.cab
O18 - Protocol: linkscanner - {F274614C-63F8-47D5-A4D1-FBDDE494F8D1} - C:\Program Files\AVG\AVG8\avgpp.dll
O20 - Winlogon Notify: avgrsstarter - C:\WINDOWS\SYSTEM32\avgrsstx.dll
O23 - Service: ACT! Scheduler - Sage Software, Inc. - C:\Program Files\ACT\Act for Windows\Act.Scheduler.exe
O23 - Service: Apple Mobile Device - Apple, Inc. - C:\Program Files\Common Files\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
O23 - Service: Autodesk Licensing Service - Autodesk - C:\Program Files\Common Files\Autodesk Shared\Service\AdskScSrv.exe
O23 - Service: AVG8 WatchDog (avg8wd) - AVG Technologies CZ, s.r.o. - C:\PROGRA~1\AVG\AVG8\avgwdsvc.exe
O23 - Service: Bonjour Service - Apple Inc. - C:\Program Files\Bonjour\mDNSResponder.exe
O23 - Service: FLEXnet Licensing Service - Macrovision Europe Ltd. - C:\Program Files\Common Files\Macrovision Shared\FLEXnet Publisher\FNPLicensingService.exe
O23 - Service: Google Software Updater (gusvc) - Google - C:\Program Files\Google\Common\Google Updater\GoogleUpdaterService.exe
O23 - Service: HP Port Resolver - Hewlett-Packard Company - C:\WINDOWS\system32\spool\drivers\w32x86\3\HPBPRO.EXE
O23 - Service: HP Status Server - Hewlett-Packard Company - C:\WINDOWS\system32\spool\drivers\w32x86\3\HPBOID.EXE
O23 - Service: iPod Service - Apple Inc. - C:\Program Files\iPod\bin\iPodService.exe
O23 - Service: mental ray 3.6 Satellite for Autodesk 3ds Max 2008 32-bit 32-bit (mi-raysat_3dsMax2008_32) - Unknown owner - C:\Program Files\Autodesk\3ds Max 2008\mentalray\satellite\raysat_3dsMax2008_32server.exe
O23 - Service: Protexis Licensing V2 (PSI_SVC_2) - Protexis Inc. - C:\Program Files\Common Files\Protexis\License Service\PsiService_2.exe
O23 - Service: TabletService - Wacom Technology, Corp. - C:\WINDOWS\system32\Tablet.exe
O23 - Service: Viewpoint Manager Service - Viewpoint Corporation - C:\Program Files\Viewpoint\Common\ViewpointService.exe

--
End of file - 8747 bytes

Hello.

• Open HijackThis
  
• Choose "Do a system scan only"
  
• Check the boxes in front of these lines:
  
  
  R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page =
  O2 - BHO: Act.UI.InternetExplorer.Plugins.AttachFile.CAttachFile - {D5233FCD-D258-4903-89B8-FB1568E7413D} - mscoree.dll (file missing)
  O9 - Extra button: Attach Web page to ACT! contact - {6F431AC3-364A-478b-BBDB-89C7CE1B18F6} - mscoree.dll (file missing)
  O9 - Extra 'Tools' menuitem: Attach Web page to ACT! contact... - {6F431AC3-364A-478b-BBDB-89C7CE1B18F6} - mscoree.dll (file missing)
  
  
  
  
• Press "Fix Checked"
  
• Close Hijack This.
  

Please download and run this tool.

Download Malwarebytes' Anti-Malware from Here

Double Click mbam-setup.exe to install the application.

• Make sure a checkmark is placed next to Update Malwarebytes' Anti-Malware and Launch Malwarebytes' Anti-Malware, then click Finish.
  
• If an update is found, it will download and install the latest version.
  
• Once the program has loaded, select "Perform Quick Scan", then click Scan.
  
• The scan may take some time to finish,so please be patient.
  
• When the scan is complete, click OK, then Show Results to view the results.
  
• Make sure that everything is checked, and click Remove Selected.
  
• When disinfection is completed, a log will open in Notepad and you may be prompted to Restart. (See Note)
  
• The log is automatically saved by MBAM and can be viewed by clicking the Logs tab in MBAM.
  

Note:
If MBAM encounters a file that is difficult to remove, you will be presented with 1 of 2 prompts.
Click OK to either and let MBAM proceed with the disinfection process.
If asked to restart the computer, please do so immediately.

Post the contents of the MBAM Log.