Malware popups issue

How is the machine now? still having problems?

Yes, doesn't seem like anything's changed.

My computer is now telling me I have UACD.sys

I also seem to have something called "System Defender" installed on my system

Ok, this is currently the situation. I can no longer start my system normally, I have to start in safemode. When I star normally there is a blue screen and it says stuff like "explorer stopped working". In safe mode almost all my regular settings are no longer there. I can't run malware bytes without an error, I tried running combofix and it told me that CFScript was not correct or something.

What does the MBAM error say?

This shortcut is no longer located here, or something. I tried uninstalling and reinstalling and when I try to run mbam I get an hourglass cursor for a moment and then nothing. I have tried renaming the executable, and same thing happened

Tried some more scanning utilities I have on the machine. nȯne of these will even open: AdAware, Spybot, AVG, HijackThis, MBAM, and Windows Defender

Finally got HijackThis to work, here's my log. HijackThis kept telling me my system would not allow acess to the host folder

Logfile of Trend Micro HijackThis v2.0.2
Scan saved at 8:25:52 PM, on 12/3/2009
Platform: Windows Vista SP2 (WinNT 6.00.1906)
MSIE: Internet Explorer v7.00 (7.00.6002.18005)
Boot mode: Safe mode with network support

Running processes:
C:\Windows\Explorer.EXE
C:\Program Files\Windows Media Player\wmpnscfg.exe
C:\Windows\system32\igfxsrvc.exe
C:\Windows\system32\config\systemprofile\AppData\Local\Temp\system.exe
C:\Windows\system32\config\systemprofile\AppData\Local\Temp\setup.exe
C:\Program Files\Internet Explorer\iexplore.exe
C:\Program Files\secret\HijackThis.exe

R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page =
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://go.microsoft.com/fwlink/?LinkId=54896
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://go.microsoft.com/fwlink/?LinkId=69157
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant =
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,CustomizeSearch =
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Local Page =
R0 - HKCU\Software\Microsoft\Internet Explorer\Toolbar,LinksFolderName =
R3 - Default URLSearchHook is missing
O1 - Hosts: ::1 localhost
O1 - Hosts: ::1 localhost
O2 - BHO: C:\Windows\system32\eqq22vk.dll - {B45A4B16-23F2-41AD-F4E4-00AAC39C0004} - C:\Windows\system32\eqq22vk.dll
O4 - HKLM\..\Run: [Windows Defender] %ProgramFiles%\Windows Defender\MSASCui.exe -hide
O4 - HKLM\..\Run: [RtHDVCpl] RtHDVCpl.exe
O4 - HKLM\..\Run: [VolPanel] "C:\Program Files\Creative\SBAudigy\Volume Panel\VolPanlu.exe" /r
O4 - HKLM\..\Run: [UpdReg] C:\Windows\UpdReg.EXE
O4 - HKLM\..\Run: [AVG8_TRAY] C:\PROGRA~1\AVG\AVG8\avgtray.exe
O4 - HKLM\..\Run: [XboxStat] "C:\Program Files\Microsoft Xbox 360 Accessories\XboxStat.exe" silentrun
O4 - HKLM\..\Run: [Adobe Reader Speed Launcher] "C:\Program Files\Adobe\Reader 8.0\Reader\Reader_sl.exe"
O4 - HKLM\..\Run: [IgfxTray] C:\Windows\system32\igfxtray.exe
O4 - HKLM\..\Run: [HotKeysCmds] C:\Windows\system32\hkcmd.exe
O4 - HKLM\..\Run: [Persistence] C:\Windows\system32\igfxpers.exe
O4 - HKLM\..\Run: [NeroFilterCheck] C:\Windows\system32\NeroCheck.exe
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\QTTask.exe" -atboottime
O4 - HKLM\..\Run: [iTunesHelper] "C:\Program Files\iTunes\iTunesHelper.exe"
O4 - HKLM\..\Run: [StartCCC] "C:\Program Files\ATI\ATI.ACE\Core-Static\CLIStart.exe" MSRun
O4 - HKLM\..\Run: [Adobe ARM] "C:\Program Files\Common Files\Adobe\ARM\1.0\AdobeARM.exe"
O4 - HKLM\..\Run: [Malwarebytes Anti-Malware (reboot)] "C:\Program Files\Malwarebytes' Anti-Malware\mbam.exe" /runcleanupscript
O4 - HKLM\..\Run: [SunJavaUpdateSched] "C:\Program Files\Java\jre6\bin\jusched.exe"
O4 - HKLM\..\Run: [System Defender] "C:\ProgramData\e17e17e\WSe17e.exe" /s /d
O4 - HKLM\..\Run: [calc] rundll32.exe C:\Windows\system32\calc.dll,_IWMPEvents@0
O4 - HKLM\..\Run: [raluvizef] Rundll32.exe "c:\windows\system32\juvuselu.dll",a
O4 - HKLM\..\Run: [jawironaza] Rundll32.exe "folajese.dll",s
O4 - HKLM\..\RunOnce: [GrpConv] grpconv -o
O4 - HKLM\..\RunOnce: [Malwarebytes' Anti-Malware] C:\Program Files\mb-am\mbamgui.exe /install /silent
O4 - HKCU\..\Run: [calc] rundll32.exe C:\Windows\system32\config\SYSTEM~1\ntuser.dll,_IWMPEvents@0
O4 - HKCU\..\Run: [jsh87r3huiehf89esiudgd] C:\Windows\TEMP\yjs68wd3.exe
O4 - HKCU\..\Run: [asg984jgkfmgasi8ug98jgkfgfb] C:\Windows\system32\config\systemprofile\AppData\Local\Temp\system.exe
O4 - HKCU\..\Run: [WMPNSCFG] C:\Program Files\Windows Media Player\WMPNSCFG.exe
O4 - HKUS\S-1-5-18\..\Run: [calc] rundll32.exe C:\Windows\system32\config\SYSTEM~1\ntuser.dll,_IWMPEvents@0 (User 'SYSTEM')
O4 - HKUS\S-1-5-18\..\Run: [jsh87r3huiehf89esiudgd] C:\Windows\TEMP\yjs68wd3.exe (User 'SYSTEM')
O4 - HKUS\S-1-5-18\..\Run: [asg984jgkfmgasi8ug98jgkfgfb] C:\Windows\system32\config\systemprofile\AppData\Local\Temp\system.exe (User 'SYSTEM')
O4 - HKUS\S-1-5-18\..\Run: [WMPNSCFG] C:\Program Files\Windows Media Player\WMPNSCFG.exe (User 'SYSTEM')
O4 - HKUS\.DEFAULT\..\Run: [calc] rundll32.exe C:\Windows\system32\config\SYSTEM~1\ntuser.dll,_IWMPEvents@0 (User 'Default user')
O7 - HKCU\Software\Microsoft\Windows\CurrentVersion\Policies\System, DisableRegedit=1
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~3\OFFICE11\EXCEL.EXE/3000
O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - (no file)
O9 - Extra 'Tools' menuitem: Sun Java Console - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - (no file)
O9 - Extra button: ieSpell - {0E17D5B7-9F5D-4fee-9DF6-CA6EE38B68A8} - C:\Program Files\ieSpell\iespell.dll
O9 - Extra 'Tools' menuitem: ieSpell - {0E17D5B7-9F5D-4fee-9DF6-CA6EE38B68A8} - C:\Program Files\ieSpell\iespell.dll
O9 - Extra button: (no name) - {1606D6F9-9D3B-4aea-A025-ED5B2FD488E7} - C:\Program Files\ieSpell\iespell.dll
O9 - Extra 'Tools' menuitem: ieSpell Options - {1606D6F9-9D3B-4aea-A025-ED5B2FD488E7} - C:\Program Files\ieSpell\iespell.dll
O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~1\MICROS~3\OFFICE11\REFIEBAR.DLL
O10 - Unknown file in Winsock LSP: c:\windows\system32\wpclsp.dll
O10 - Unknown file in Winsock LSP: c:\windows\system32\wpclsp.dll
O10 - Unknown file in Winsock LSP: c:\windows\system32\wpclsp.dll
O10 - Unknown file in Winsock LSP: c:\windows\system32\wpclsp.dll
O10 - Unknown file in Winsock LSP: c:\windows\system32\wpclsp.dll
O10 - Unknown file in Winsock LSP: c:\windows\system32\wpclsp.dll
O10 - Unknown file in Winsock LSP: c:\windows\system32\wpclsp.dll
O10 - Unknown file in Winsock LSP: c:\windows\system32\wpclsp.dll
O10 - Unknown file in Winsock LSP: c:\windows\system32\wpclsp.dll
O13 - Gopher Prefix:
O16 - DPF: {3860DD98-0549-4D50-AA72-5D17D200EE10} (Windows Live OneCare safety scanner control) - http://cdn.scan.onecare.live.com/resource/download/scanner/en-US/wlscctrl2.cab
O16 - DPF: {39B0684F-D7BF-4743-B050-FDC3F48F7E3B} - http://www.fileplanet.com/fpdlmgr/cabs/FPDC_2.3.7.109.cab
O18 - Protocol: linkscanner - {F274614C-63F8-47D5-A4D1-FBDDE494F8D1} - C:\Program Files\AVG\AVG8\avgpp.dll
O18 - Protocol: skype4com - {FFC8B962-9B40-4DFF-9458-1830C7DD7F5D} - C:\PROGRA~1\COMMON~1\Skype\SKYPE4~1.DLL
O20 - AppInit_DLLs: C:\Windows\System32\curslib.dll,ribayiro.dll
O20 - Winlogon Notify: __c007EE14 - C:\Windows\system32\__c007EE14.dat
O21 - SSODL: dalelamit - {4d05a1ab-de47-440c-82d5-36ba7554fe9d} - c:\windows\system32\juvuselu.dll
O22 - SharedTaskScheduler: jkshf8a3rudbfa873fudfhbdugf87whjdb - {B45A4B16-23F2-41AD-F4E4-00AAC39C0004} - C:\Windows\system32\eqq22vk.dll
O22 - SharedTaskScheduler: tokatiluy - {4d05a1ab-de47-440c-82d5-36ba7554fe9d} - c:\windows\system32\juvuselu.dll
O23 - Service: Lavasoft Ad-Aware Service (aawservice) - Lavasoft - C:\Program Files\Lavasoft\Ad-Aware\aawservice.exe
O23 - Service: AMD External Events Utility - AMD - C:\Windows\system32\atiesrxx.exe
O23 - Service: Apple Mobile Device - Apple Inc. - C:\Program Files\Common Files\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
O23 - Service: AVG Free8 WatchDog (avg8wd) - AVG Technologies CZ, s.r.o. - C:\PROGRA~1\AVG\AVG8\avgwdsvc.exe
O23 - Service: Bonjour Service - Apple Inc. - C:\Program Files\Bonjour\mDNSResponder.exe
O23 - Service: Creative Labs Licensing Service - Creative Labs - C:\Program Files\Common Files\Creative Labs Shared\Service\CreativeLicensing.exe
O23 - Service: Creative Service for CDROM Access - Creative Technology Ltd - C:\Windows\system32\CTsvcCDA.exe
O23 - Service: dldf_device - - C:\Windows\system32\dldfcoms.exe
O23 - Service: fastnetsrv Service (fastnetsrv) - Netopsystems A - C:\Windows\system32\FastNetSrv.exe
O23 - Service: iPod Service - Apple Inc. - C:\Program Files\iPod\bin\iPodService.exe
O23 - Service: Nero BackItUp Scheduler 4.0 - Nero AG - C:\Program Files\Common Files\Nero\Nero BackItUp 4\NBService.exe
O23 - Service: PEVSystemStart - Unknown owner - C:\ComboFix\PEV.cfxxe (file missing)
O23 - Service: PnkBstrA - Unknown owner - C:\Windows\system32\PnkBstrA.exe
O23 - Service: Steam Client Service - Valve Corporation - C:\Program Files\Common Files\Steam\SteamService.exe
O23 - Service: stllssvr - MicroVision Development, Inc. - C:\Program Files\Common Files\SureThing Shared\stllssvr.exe
O23 - Service: Viewpoint Manager Service - Viewpoint Corporation - C:\Program Files\Viewpoint\Common\ViewpointService.exe

--
End of file - 8611 bytes

Your system is severly infected. Problem with these infections nowadays is, it causes a lot of damage. Even if we clean the malware off your system, I can't guarantee that your system will be clean afterwards, because these infections/bundles leave a lot of leftovers behind that most scanners won't even recognise and logs won't show.
Also, I can't promise you we can repair all the damage it caused... Even after cleaning the malware, you can still get errors afterwards because of the damage. Solving these is not always possible since it will be searching for a needle in a haystack to find the right cause and solution.
So, we can try to clean this up and do what we can, but keep in mind that we can't solve ALL problems this malware already caused.

In light of this it would be wise for you to back up any files and folders that you don't want to lose before we start. Reason I am telling this is because when a system is so terribly infected and we try to clean this up manually, the damage that is already present may interfere with our removal attempts.

• Open HijackThis
  
• Choose "Do a system scan only"
  
• Check the boxes in front of these lines:
  
  
  R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page =
  R3 - Default URLSearchHook is missing
  O1 - Hosts: ::1 localhost
  O1 - Hosts: ::1 localhost
  O2 - BHO: C:\Windows\system32\eqq22vk.dll - {B45A4B16-23F2-41AD-F4E4-00AAC39C0004} - C:\Windows\system32\eqq22vk.dll
  O4 - HKLM\..\Run: [System Defender] "C:\ProgramData\e17e17e\WSe17e.exe" /s /d
  O4 - HKLM\..\Run: [calc] rundll32.exe C:\Windows\system32\calc.dll,_IWMPEvents@0
  O4 - HKLM\..\Run: [raluvizef] Rundll32.exe "c:\windows\system32\juvuselu.dll",a
  O4 - HKLM\..\Run: [jawironaza] Rundll32.exe "folajese.dll",s
  O4 - HKLM\..\RunOnce: [GrpConv] grpconv -o
  O4 - HKLM\..\RunOnce: [Malwarebytes' Anti-Malware] C:\Program Files\mb-am\mbamgui.exe /install /silent
  O4 - HKCU\..\Run: [calc] rundll32.exe C:\Windows\system32\config\SYSTEM~1\ntuser.dll,_IWMPEvents@0
  O4 - HKCU\..\Run: [jsh87r3huiehf89esiudgd] C:\Windows\TEMP\yjs68wd3.exe
  O4 - HKCU\..\Run: [asg984jgkfmgasi8ug98jgkfgfb] C:\Windows\system32\config\systemprofile\AppData\Local\Temp\system.exe
  O4 - HKUS\S-1-5-18\..\Run: [calc] rundll32.exe C:\Windows\system32\config\SYSTEM~1\ntuser.dll,_IWMPEvents@0 (User 'SYSTEM')
  O4 - HKUS\S-1-5-18\..\Run: [jsh87r3huiehf89esiudgd] C:\Windows\TEMP\yjs68wd3.exe (User 'SYSTEM')
  O4 - HKUS\S-1-5-18\..\Run: [asg984jgkfmgasi8ug98jgkfgfb] C:\Windows\system32\config\systemprofile\AppData\Local\Temp\system.exe (User 'SYSTEM')
  O4 - HKUS\.DEFAULT\..\Run: [calc] rundll32.exe C:\Windows\system32\config\SYSTEM~1\ntuser.dll,_IWMPEvents@0 (User 'Default user')
  O7 - HKCU\Software\Microsoft\Windows\CurrentVersion\Policies\System, DisableRegedit=1
  O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - (no file)
  O9 - Extra 'Tools' menuitem: Sun Java Console - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - (no file)
  O20 - AppInit_DLLs: C:\Windows\System32\curslib.dll,ribayiro.dll
  O20 - Winlogon Notify: __c007EE14 - C:\Windows\system32\__c007EE14.dat
  O21 - SSODL: dalelamit - {4d05a1ab-de47-440c-82d5-36ba7554fe9d} - c:\windows\system32\juvuselu.dll
  O22 - SharedTaskScheduler: jkshf8a3rudbfa873fudfhbdugf87whjdb - {B45A4B16-23F2-41AD-F4E4-00AAC39C0004} - C:\Windows\system32\eqq22vk.dll
  O22 - SharedTaskScheduler: tokatiluy - {4d05a1ab-de47-440c-82d5-36ba7554fe9d} - c:\windows\system32\juvuselu.dll
  
  
  
• Press "Fix Checked"
  
• Close Hijack This.
  

Please download and run this tool.

Download Malwarebytes' Anti-Malware from Here

Double Click mbam-setup.exe to install the application.

• Make sure a checkmark is placed next to Update Malwarebytes' Anti-Malware and Launch Malwarebytes' Anti-Malware, then click Finish.
  
• If an update is found, it will download and install the latest version.
  
• Once the program has loaded, select "Perform Quick Scan", then click Scan.
  
• The scan may take some time to finish,so please be patient.
  
• When the scan is complete, click OK, then Show Results to view the results.
  
• Make sure that everything is checked, and click Remove Selected.
  
• When disinfection is completed, a log will open in Notepad and you may be prompted to Restart. (See Note)
  
• The log is automatically saved by MBAM and can be viewed by clicking the Logs tab in MBAM.
  

Note:
If MBAM encounters a file that is difficult to remove, you will be presented with 1 of 2 prompts.
Click OK to either and let MBAM proceed with the disinfection process.
If asked to restart the computer, please do so immediately.

Post the contents of the MBAM Log.

In light of what you said and the fact that I already backed up everything on my system I just decided to reformat the drive. Thank you for all your help.