AV Security suite beat NOD32

My inlaws are running a Dell PC with Win Vista and NOD32. They have an infection of AV Security Suite. I checked the NOD32 update and it is the most current release, a bit irritated that the infection got past. I read through various posts and pages and found several references to manual removal and registry edits. Booted in safe mode with networking. Removed the browser proxy settings but when I looked for the Documents and Settings folder it was not there. I disabled the network card and ran Malwarebytes last night, was running when I left their house. Will return this afternoon to see what the results are. My main concern is that I am running the same NOD32 on my laptop and home PC, if this program won't stop viruses what would be a better choice?

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Seems as if it got past NOD32, because it was installed by choice, instead of accidentally.

Please visit this webpage for a tutorial on downloading and running ComboFix:

http://www.bleepingcomputer.com/combofix/how-to-use-combofix

See the area: Using ComboFix, and when done, post the log back here.